ENZYME-LINKED IMMUNOSORBENT-ASSAY FOR CIRCULATING ANTI-GLOMERULAR BASEMENT-MEMBRANE ANTIBODIES
- 1 January 1981
- journal article
- research article
- Vol. 45 (2) , 271-278
Abstract
An enzyme-linked immunosorbent assay for the quantitative determination of anti-glomerular basement membrane antibodies in human sera, which is sensitive and reproducible, is described. The test detected circulating antibodies in 7 patients with active anti-glomerular basement membrane disease; sera from 42 patients, with a variety of other glomerulonephropathies, were negative by the test. A good correlation was demonstrated between the levels of circulating anti-glomerular basement membrane antibodies and the clinical course of disease in 1 patient with Goodpasture''s syndrome.This publication has 13 references indexed in Scilit:
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