Effects of Erythromycin, Aminoglucosides and Doxycycline on Mucociliary Activity in vitro of Rabbit Trachea
- 1 January 1983
- journal article
- research article
- Published by S. Karger AG in Pharmacology
- Vol. 26 (1) , 40-45
- https://doi.org/10.1159/000137767
Abstract
The effect of different antibiotics [penicillins] on the mucociliary activity of the upper respiratory tract of rabbit was tested in vitro. Erythromycin base had no effect, although erythromycin lactobionate had a minor inhibitory effect. Kanamycin and gentamicin had no inhibitory effect in high concentrations. Doxycycline had the highest mucociliary inhibitory effect; however, the toxic concentrations are > 10 times the clinically relevant serum levels after oral administration.This publication has 5 references indexed in Scilit:
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