Biliary Glycoprotein I (BGP I), a CEA‐crossreactive Substance: Purification and Properties

Abstract
A CEA‐crossreactive substance was purified from human bile. It was termed biliary glycoprotein I (BGPI). The molecular weight of BGP I is about 90,000. The protein part is made up of a single polypeptide chain with a composition similar to that of CEA and NCA. BGP I contains the same monosaccharides as CEA and NCA and shows a similar lectin reactivity. BGP I has antigenic determinants in common with CEA and NCA. In addition it contains unique determinants.

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