Structure of Curcumol

Abstract
Extraction of zedoary (Curcuma zedoaria (Zingibera-ceae)) has afforded a new sesquiterpenoid, curcumol, of the empirical formula C15H24O2. It contains a vinylidene group and a hemiketal system. The guaiane carbon skeleton was established by its dehydrogenation giving S-guaiazulene. Curcumol has been ozonized to give the norketone which was converted into the acid and the lactone. Spectroscopic study of these derivatives and other evidence show curcumol to be represented by formula I (R = H).

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