Redefined Role of Radiation in Combined Treatment of Ewing's Sarcoma
- 1 January 1986
- journal article
- research article
- Published by Taylor & Francis in Pediatric Hematology and Oncology
- Vol. 3 (2) , 111-118
- https://doi.org/10.3109/08880018609031206
Abstract
Eighty-six patients with Ewing 's sarcoma were analyzed as to the role of radiation therapy. Fifty-eight patients (P group) had removal of the involved part of the bone after preoperative chemotherapy, and 28 (NP group) had local treatment either at the same time or before chemotherapy. Thirty-six of 58 P-group patients (61 %) and 13 of the 28 NP-group patients (48%) are alive. Five of 48 patients in P group, who had postoperative radiation, had local recurrence, as did 6 of 11 without postoperative radiation, a statistically significant difference (p = 0.001).Keywords
This publication has 17 references indexed in Scilit:
- Intensive systemic chemotherapy in localized Ewing's sarcoma in childhood. A historical trialCancer, 1983
- The response of Ewing's sarcoma to sequential cyclophosphamide and adriamycin induction therapy.Journal of Clinical Oncology, 1983
- Curability of ewing's sarcoma and considerations for future therapeutic trialsCancer, 1978
- Improved outlook for Ewing's sarcoma with combination chemotherapy (vincristine, actinomycin D and cyclophosphamide) and radiation therapyCancer, 1976
- Acute and late effects on normal tissues following combined chemo- and radiotherapy for childhood rhabdomyosarcoma and Ewing's sarcomaCancer, 1976
- Ewingʼs sarcoma. A clinicopathological and statistical analysis of patients surviving five years or longerJournal of Bone and Joint Surgery, 1975
- Treatment of clinically localized Ewing's sarcoma with radiotherapy and combination chemotherapyCancer, 1972
- Past failures and future possibilities in Ewing's sarcoma:Experimental and preliminary clinical resultsCancer, 1969
- Ewing's sarcoma.Case against surgeryCancer, 1967
- Ewing's SarcomaNew England Journal of Medicine, 1953