Co-Expression of CD2 or CD8 Antigens in B-Cell Chronic Lymphocytic Leukaemia

Abstract
Three cases of biphenotypic CD2 or CDS positive chronic lymphocytic B-cell leukaemias are reported. This represents an incidence of 15% in the authors’ scries, a frequency never mentioned previously. CD2 expression could be an example of asynchronous expression of an early pre-B antigen. CD8 expression might probe a true mixed lineage phenotype. These aberrrant phenotypes were not associated with any peculiar clinical presentation.

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