Association of hypogonadism and type II diabetes in men attending an outpatient erectile dysfunction clinic
Open Access
- 1 September 2005
- journal article
- research article
- Published by Springer Nature in International Journal Of Impotence Research
- Vol. 18 (2) , 190-197
- https://doi.org/10.1038/sj.ijir.3901391
Abstract
Patients with diabetes mellitus (DM) were more often hypogonadal than normal fasting glucose subjects. The aim of this investigation is the assessment of characteristics and psychobiological correlates of DM associated with hypogonadism (DMAH). The Structured Interview SIEDY© was used along with several biochemical, psychological and instrumental investigations in a series of more than 1200 patients with erectile dysfunction (ED); 16% of whom with type II DM. Hypogonadism was defined as circulating total testosterone (T) below 10.4 nmol/l. The prevalence of hypogonadism was 24.5% in DM versus 12.6% in the rest of the sample (P1 injection) peak systolic velocity and acceleration, when compared to the rest of the sample, even after adjustment for age and BMI. Our results show that hypogonadism is frequently associated with type II DM, at least in the 6th decade. DMAH might exacerbate sexual dysfunction by reducing libido and mood and further compromising penile vascular reactivity.Keywords
This publication has 38 references indexed in Scilit:
- Testosterone Regulates PDE5 Expression and in vivo Responsiveness to Tadalafil in Rat Corpus CavernosumEuropean Urology, 2004
- Organic, Relational and Psychological Factors in Erectile Dysfunction in Men with Diabetes MellitusEuropean Urology, 2004
- RANDOMIZED STUDY OF TESTOSTERONE GEL AS ADJUNCTIVE THERAPY TO SILDENAFIL IN HYPOGONADAL MEN WITH ERECTILE DYSFUNCTION WHO DO NOT RESPOND TO SILDENAFIL ALONEJournal of Urology, 2004
- Association of Bioavailable, Free, and Total Testosterone With Insulin ResistanceDiabetes Care, 2004
- Depression in Aging MenDrugs & Aging, 2004
- Optimizing Treatment for Diabetes Mellitus Induced Erectile DysfunctionJournal of Urology, 2003
- Structured interview on erectile dysfunction (SIEDY©): a new, multidimensional instrument for quantification of pathogenetic issues on erectile dysfunctionInternational Journal Of Impotence Research, 2003
- Role of Brain Insulin Receptor in Control of Body Weight and ReproductionScience, 2000
- The hypogonadal–obesity cycle: role of aromatase in modulating the testosterone–estradiol shunt – a major factor in the genesis of morbid obesityMedical Hypotheses, 1999
- Proceedings of a consensus development conference on standardized measures in diabetic neuropathyMuscle & Nerve, 1992