SUCCESSFUL TREATMENT OF ACUTE DAPSONE INTOXICATION USING CHARCOAL HEMOPERFUSION
- 1 October 1983
- journal article
- case report
- Published by Wiley in Australian and New Zealand Journal of Medicine
- Vol. 13 (5) , 509-512
- https://doi.org/10.1111/j.1445-5994.1983.tb02704.x
Abstract
A 22 year old female was admitted to hospital two hours after ingesting 4 g of dapsone. Over the next 15 h she developed progressive hemolysis and methemoglobinemia. Charcoal hemoper‐fusion and sequential dialysis were performed because of the serious risk of fatality following such a massive dose of dapsone. Charcoal hemoperfusion led to rapid clearing of dapsone from the circulation. This resulted in clinical improvement and controlled the progression of hemolysis and methemoglobinemia.Keywords
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