Conformation of Poly-L-methionine in Solution

Abstract
A study of poly-L-methionine by viscosity, light-scattering, and NMR spectroscopy shows 1) that the helical rodhke form of the polypeptide has approximately the same dimensions as helical poly-γ-benzyl-L-glutamate, and 2) that the random coil form in trifluoroacetic acid is charged and fits the same Mark-Houwink equation as does poly-γ-benzyl-L-glutamate in dichloroacetic acid. The relationships between NMR Line widths and degree of polymerization is given for three different polypeptides.

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