Pyridine-2-aldehyde 2-furoylhydrazone as a fluorogenic reagent for the determination of nanogram amounts of gallium

Abstract
The synthesis, characteristics and analytical applications of pyridine-2-aldehyde 2-furoylhydrazone (PAFH) are described. This compound has been examined to evaluate its usefulness as a selective and sensitive spectrofluorimetric reagent for gallium. The method is applied in 0.8% ethanolic solution at pH 4.5. Under these conditions the fluorescent species have excitation and emission maxima at 380 and 445 nm, respectively. The detection limit is 0.8 ng ml–1 and the range of application is between 1 and 50 ng ml–1. The method has been employed to determine gallium in synthetic mixtures and its recovery from human urine samples.

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