Biosynthesis of sclerin, a metabolite of Sclerotinia sclerotiorum: incorporation of [1-13C]- and [1,2-13C2]-acetates

Abstract
Sclerin, a metabolite of Sclerotinia sclerotiorum, incorporates five intact acetate units; the results are in accord with a biosynthesis from two separately formed polyketide chains but an alternative pathway involving a single polyketide chain is proposed.

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