Contact dermatitis to semisynthetic penicillins in factory workers

Abstract
45 workers developed dermatitis after handling semi-synthetic penicillins in a factory. All reacted on patch lest, but several agents had to be used. Only 7 reacted to benzyl penicillin. 1/2 reacted to only one allergen, while 2/3 reacted to several. The duration of exposure before symptoms was short, often less than 2 months, 19 had hay lever or asthma, and they developed their symptoms after a shorter exposure time. A survey for airborne antibiotics was performed.

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