Hypothalamic Sarcoidosis and Hypopituitarism
- 1 January 1980
- journal article
- case report
- Published by S. Karger AG in Hormone Research
- Vol. 12 (1) , 1-9
- https://doi.org/10.1159/000179099
Abstract
4 patients with presumed pituitary hypothalamic sarcoidosis are described. 3 had histological diagnoses compatible with sarcoidosis and in the other this diagnosis was strongly suspected from chest X-rays. 2 patients presented with diabetes insipidus. ACTH reserve was diminished in 3 out of 4 and growth hormone reserve was diminished in the 3 who were tested. All 4 patients developed secondary amenorrhea. 3 patients had hypothalamic hypothyroidism. Prolactin dynamics were intact. Tomograms of the sella turcica in all 4 and computerized tomography of the hypothalamic area in 2 patients failed to reveal any abnormality.Keywords
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