Posterior Precortical Vitreous Pocket-Reply

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Abstract
In Reply.—We concur with Dr Sebag's view that the PPVP reflects age-related vitreous liquefaction that starts in the premacular region. Still, the morphologic characteristics of the PPVP are so specific in shape and location that it is inappropriate to identify it as simply a result of premacular vitreous liquefaction.We observed an oval defect in the premacular vitreous cortex only in eyes with posterior vitreous detachment. The vitreous gel may herniate through this hole into the retrohyaloid space. This feature is frequently seen even in vivo. The anterioposteriorly arrayed vitreous fibers seem to run toward the posterior pole but with ill-defined termination. The vitreous gel is separated from the cortex by the intervening PPVP at the macula before posterior vitreous detachment begins. Therefore, we do not believe that the vitreous fibers passing through the defect are anchored to the premacular vitreous cortex and exert traction to the macula.See

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