Histological, Histochemical, and Ultrastructural Aspects of Interstitial Tissue from the Contralateral Testis in Infertile Men with Monolateral Varicocele

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Abstract
Initial maturative arrest, thickening of the tubular wall, and involution-degeneration of the Leydig cells are the most frequent lesions observed in contralateral testis in men affected by monolateral varicocele. Alterations observed in the Leydig cells at the electron microscope appear to support the hypothesis of hyperstimulation of the cells with rapid degeneration.