Abstract
IN medicine, we are constantly challenged by new syndromes or by new manifestations of known syndromes. In this issue of the Journal, two groups, Davis and his co-workers from Wisconsin and Shands and her associates from the Center for Disease Control, describe an important new disease, toxic-shock syndrome (TSS). More than 300 cases have already been identified in the United States during the current year. These cases have occurred predominantly in menstruating women; they are characterized by sudden onset of fever, diarrhea, shock, a diffuse macular erythematous rash followed by desquamation from the hands and feet, and hyperemia of . . .

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