Alterations in DNA methylation in human colon neoplasia
- 1 January 1987
- journal article
- research article
- Published by Wiley in Seminars in Surgical Oncology
- Vol. 3 (3) , 149-151
- https://doi.org/10.1002/ssu.2980030304
Abstract
A review of studies on DNA methylation in colonic neoplasia is presented. Hypomethylation of a wide variety of genes from throughout the genome was seen in all colon cancers studied. These changes preceded malignancy because benign adenomas were also affected.Keywords
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