SUPPRESSIVE FACTOR AGAINST MACROPHAGE PHAGOCYTOSIS PRODUCED BY CULTURED SARCOMA-180 CELLS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 70  (5) , 671-675
Abstract
A soluble factor which suppresses phagocytic ability of macrophages against Staphylococcus aureus, as well as latex particles, was found in the culture supernatant of sarcoma-180 cells. This factor was stable to heating at 56.degree. C for 30 min and had a MW of more than 10,000. Supernatant from normal spleen cell culture also showed some antiphagocytic activity but it was considerably lower than that of sarcoma-180 cell culture.

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