ENHANCEMENT OF TUMOR-GROWTH FOLLOWING IMMUNIZATION WITH BACILLUS-CALMETTE-GUERIN CELL-WALLS

  • 1 January 1976
    • journal article
    • research article
    • Vol. 36  (6) , 1950-1953
Abstract
The effect of preimmunization with BCG cell walls (BCGcw) on tumor growth was studied with the use of transplantable Morris Hepatoma 3924a in inbred ACl rats. There was an increase in tumor incidence, an increase in i.m. tumor growth rate and an increase in the average i.m. tumor mass in animals preimmunized with BCGcw. The BCGcw-induced enhancement in tumor growth was dependent on the amount of tumor present at the time of BCGcw immunization. No enhancement occurred in animals immunized with BCGcw 12 days after inoculation of tumor cells.

This publication has 1 reference indexed in Scilit: