In utero Epstein-Barr virus (infectious mononucleosis) infection
- 2 October 1981
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 246 (14) , 1579-1581
- https://doi.org/10.1001/jama.246.14.1579
Abstract
A male infant infected in utero with Epstein-Barr virus (EBV) demonstrated a syndrome of multiple congenital anomalies (micrognathia, cryptorchidism, central cataracts), hypotonia, thrombocytopenia, persistent monocytosis, proteinuria, and multiple areas of metaphysitis at birth. Lymphocytes were Epstein-Barr nuclear antigen (EBNA) positive (18%) and persisted in culture for three months. He had antibody to early antigen (anti-EA), IgM-viral capsid (anti-VCA), and EBNA (anti-EBNA) detectable at 22 days of age. All attempts to isolate infectious agents or to serologically identify other infectious causes for his syndrome were negative. (JAMA1981;246:1579-1581)This publication has 1 reference indexed in Scilit: