REVERSION OF B-BAR TO A-BAR TRANSITION IN DNA BY BIS-(2-GUANIDOETHYL)DISULFIDE

  • 1 January 1982
    • journal article
    • letter
    • Vol. 27  (2) , 322-324
Abstract
Transition from .hivin.B to .hivin.A form of DNA in water/ethanol solutions is hindered by stoichiometric quantities of a bifunctional cation, bis(2-guanidoethyl)disulfide (GED). Using data on the shift and widening of the .hivin.B-.hivin.A transition curves in the presence of GED, a value on the order of 10 base pairs was estimated for the cooperativity length of the .hivin.B-.hivin.A transition which agrees well with values obtained earlier.

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