THE EFFECTS OF AN ANTI-PROGESTERONE STEROID IN WOMEN - INTERRUPTION OF THE MENSTRUAL-CYCLE AND OF EARLY-PREGNANCY

  • 1 January 1982
    • journal article
    • research article
    • Vol. 294  (18) , 933-938
Abstract
RU-486 is a steroid which possesses a great affinity for the progesterone receptor, does not have a progesterone activity, but is indeed a strong antagonist of progesterone effects in animals [rats and rabbits]. Oral administration induces the interruption of the luteal phase of the menstrual cycle and that of early pregnancy in women. Its mode of administration and its properties enable one to envisage a new methodology for menstrual cycle regulation and human birth control.

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