Thyroxine Inhibition of the Proliferative Response of the Anterior Pituitary to Thyrotropin Releasing Hormone in vitro

1 January 1975

journal article
Published by S. Karger AG in Neuroendocrinology

Vol. 18 (3) , 277-280
https://doi.org/10.1159/000122407

Abstract

TRH increased cell proliferation in organ-cultured rat adenohypophysis. Thyroxine by itself had no effect on adenohypophysial cell proliferation in vitro but inhibited the mitogenic effect of TRH.

Keywords

ADENOHYPOPHYSIAL CELL
PROLIFERATIVE RESPONSE
VITRO TRH
THYROTROPIN RELEASING
RAT ADENOHYPOPHYSIS
NO EFFECT
ANTERIOR PITUITARY
TRH INCREASED
MITOGENIC EFFECT

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