Decolorization on Freezing of Ferricyanide-Cyanide Solution used for Hemoglobin Determinations
- 1 July 1964
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 10 (7) , 611-618
- https://doi.org/10.1093/clinchem/10.7.611
Abstract
When Drabkin's solution (used for the determination of hemoglobin), which contains K3Fe(CN)6, KCN, and NaHCO3, is frozen, it loses its greenish-yellow color. The solution remains colorless even after thawing. The reaction, for which there is no satisfactory explanation, involves the reduction of the K3Fe(CN)6 to K4Fe(CN)6, with KCN being oxidized to KCNO.Keywords
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