Hydrogenation of Digitalis Genins and Anhydrogenins
- 1 September 1961
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 13 (1) , 262-267
- https://doi.org/10.1111/j.2042-7158.1961.tb11822.x
Abstract
Hydrogenation of the 14,15-unsaturated linkage in the digitalis β–anhydrogenins without simultaneous reduction of the cyclobutenolide group is described. The reduced compounds have an α configuration for the hydrogen at C(14). Hydrogenation of the cyclobutenolide ring produces two isomeric compounds which have been separated and assigned to the 20α and 20β steroid series respectively.Keywords
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