Comparison of Haloperidol and Chlorpromazine in the Treatment of Phencyclidine Psychosis
- 1 April 1984
- journal article
- research article
- Published by Wiley in The Journal of Clinical Pharmacology
- Vol. 24 (4) , 202-204
- https://doi.org/10.1002/j.1552-4604.1984.tb01831.x
Abstract
Two neuroleptics, haloperidol and chlorpromazine, have been reported to be effective in the treatment of phencyclidine (PCP) psychosis. Both neuroleptics are thought to exert their antipsychotic PCP effects by blockade of central dopamine receptors. They have been studied extensively in animal populations and less extensively in human populations. There has, however, been no comparison of their relative effects in human populations. We describe such a study below.Keywords
This publication has 7 references indexed in Scilit:
- Physostigmine and haloperidol treatment of acute phencyclidine intoxicationAmerican Journal of Psychiatry, 1982
- Phencyclidine Intoxication: Assessment of Possible AntidotesJournal of Toxicology: Clinical Toxicology, 1982
- Dopamine receptors, neuroleptics, and schizophreniaAmerican Journal of Psychiatry, 1981
- Specific [3H]phencyclidine binding in rat central nervous system.Proceedings of the National Academy of Sciences, 1979
- Interaction of phencyclidines with the muscarinic and opiate receptors in the central nervous systemBrain Research, 1978
- Thin-Layer Chromatographic Screening and Confirmation of Phencyclidine In UrineJournal of Analytical Toxicology, 1977
- The Brief Psychiatric Rating ScalePsychological Reports, 1962