A Modified Seroflocculation Reaction in Relationship to Invasive Neoplasms.

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Abstract
Following the previous description of the seroflocculation reaction brought about by mixing of the serum of a cancer-bearing patient with ethyl choladienate, the author presents a modified procedure whereby the incidences of false positives are significantly reduced; from 13% to 0.6% in normal individuals, from 38% to 10% in other pathological conditions, while the incidence of false positives in biopsy-proven invasive cancers remains essentially unchanged (93%-92%). The author suggests the seroflocculation reaction as a useful screening procedure for the detection of invasive cancer.

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