Synthesis of the hydroxyethylene dipeptide isostere, (2S,4S,5S)-5-amino-6-cyclohexyl-4-hydroxy-2-isopropyl hexanoic acid n-butyl amide
- 1 March 1992
- journal article
- Published by Elsevier in Tetrahedron Letters
- Vol. 33 (11) , 1411-1414
- https://doi.org/10.1016/s0040-4039(00)91634-4
Abstract
No abstract availableKeywords
This publication has 25 references indexed in Scilit:
- Renin inhibitorsMedicinal Research Reviews, 1990
- A versatile and stereocontrolled synthesis of hydroxyethylene dipeptide isosteresThe Journal of Organic Chemistry, 1989
- The synthesis of (2S,4S,5S) -5-(N-BOC)-amino-6-cyclohexyl-4-hydroxy-2-isopropyl-hexanoic acid lactone, an hydroxyethylene dipeptide isostere precusorTetrahedron Letters, 1989
- Synthesis of the dipeptide hydroxyethylene isostere of Leu-Val, a transition state mimic for the control of enzyme functionThe Journal of Organic Chemistry, 1988
- Synthesis and biological activity of some transition-state inhibitors of human reninJournal of Medicinal Chemistry, 1988
- Synthetic and enzyme inhibition studies of pepstatin analogs containing hydroxyethylene and ketomethylene dipeptide isosteresJournal of Medicinal Chemistry, 1987
- A short, stereoselective synthesis of the lactone precursor to 2R,4S,5S hydroxyethylene dipeptide isosteresThe Journal of Organic Chemistry, 1986
- Dipeptide analogs. Versatile synthesis of the hydroxyethylene isostereThe Journal of Organic Chemistry, 1986
- A stereocontrolled synthesis of hydroxyethylene dipeptide isosteres using novel, chiral aminoalkyl epoxides and .gamma.-(aminoalkyl)-.gamma.-lactonesThe Journal of Organic Chemistry, 1985
- Synthesis of hydroxyethylene and ketomethylene dipeptide isosteresTetrahedron Letters, 1983