Buffer Effect of Saliva in Vitro

Publisher Website
Google Scholar
Abstract
[Abstract onlyj.[long dash]Several combinations (2 salts in each) of alkali salts of carbonic- and orthophosphoric acids were made using appropriate ratios of the components to get pH 7.4 when dissolved to find suitable additives of sugars to reduce their well known property to cause dental caries. The combinations were added to aliquots of saliva (1%, w/v) that was collected during ingestion of ordinary sugar tablets. Titration with HC1 to pH 4.0 indicated that sodium bicarbonate combined with acid ammonium-, potassium- or sodium phosphate increased the buffer effect of the sugar-stimulated saliva considerably more than the combinations of phosphate salts alone. The bicarbonate -phosphate combinations, when mixed into sugar, may reduce human caries by inhibiting the formation of the low pH- and inorganic phosphate values that occur in the bacterial plaques on tooth surfaces during and after ingestion of sugar.

This publication has 0 references indexed in Scilit: