KIDNEY FUNCTION IN MORPHINE ADDICTS

11 January 1930

journal article
research article
Published by American Medical Association (AMA)

Vol. 94 (2) , 79-80
https://doi.org/10.1001/jama.1930.02710280007003

Abstract

The controversy over the effect of morphine on kidney function has long been unsettled and many physicians, particularly genito-urinary surgeons, are loath to give the drug even for severe pain, fearing that it will increase the dysfunction in an already impaired kidney. If their fears can be dispelled, their patients will derive the benefits of rest with minimized postoperative pain to aid in their recovery. Slocum's¹questionnaire brought out the conflicting opinions of surgeons generally. Ten per cent of the surgeons answering the question "Does morphine have a deleterious action on the kidney?" replied in the affirmative but did not explain why it was harmful, and 85 per cent answered in the negative. The article by Haines and Milliken²and that of Davis³showed not only that morphine might be used without fear of injuring the kidney but that morphine and atropine even accelerated and improved kidney

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