SLExexpression of normal CD 34 positive bone marrow haemopoietic progenitor cells
- 1 April 1994
- journal article
- Published by Wiley in British Journal of Haematology
- Vol. 86 (4) , 883-886
- https://doi.org/10.1111/j.1365-2141.1994.tb04850.x
Abstract
Summary. We investigated sialylated Lewis x (sLex) antigen expression on CD 34 positive (CD 34+) haemopoietic progenitors in the bone marrow of eight healthy volunteers using monoclonal antibodies. We found that in all the samples examined, CD 34+ bone marrow progenitors strongly expressed the sLex antigen. This contradicts previous publications which reported sLex expression on malignant blast cells but not on normal CD 34+ progenitor cells.Keywords
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