Aggressive natural killer (NK) cell lymphoma: report of a pediatric case and review of the literature
- 1 January 1997
- journal article
- case report
- Published by Taylor & Francis in Leukemia & Lymphoma
- Vol. 25 (3-4) , 387-392
- https://doi.org/10.3109/10428199709114178
Abstract
We report a rare pediatric case of aggressive natural killer (NK) cell lymphoma, characterized by acute onset hepatosplenomegaly and respiratory distress, and infiltration by large granular lymphocytes with the phenotype of CD3-CD16-CD56+. The patient has remained in complete remission after short-pulse intensive chemotherapy, and myeloablative therapy followed by allogeneic bone marrow transplantation. We compare our case with 7 other children with NK cell leukemia reported from other institutions.Keywords
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