Time-resolved imaging on a realistic tissue phantom: μs′ and μa images versus time-integrated images

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Abstract
A method is proposed by which we construct images through turbid media, plotting directly either the transport-scattering coefficient μs′ or the absorption coefficient μa. These optical parameters are obtained from the best fit of the time-resolved transmittance curves with a diffusion model. Measurements were performed with a time-correlated single-photon counting system on realistic tissue phantoms simulating a tumor mass within a breast. Images were obtained with an incident power of s′ and μa images with time-integrated images constructed from the same experimental data shows that the fitting method discriminates between scattering and absorption inhomogeneities and improves image quality for scattering but not for absorption inhomogeneities.