Ultastructural changes in open comedones following treatment of cystic acne with isotretinoin
- 1 June 1985
- journal article
- research article
- Published by Wolters Kluwer Health in The American Journal of Dermatopathology
- Vol. 7 (3) , 241-244
- https://doi.org/10.1097/00000372-198506000-00005
Abstract
The primary change found in cellular material expressed from open comedones of patients who had been treated with isotretinoin was disintegration of desmosomes. Consequently, there was lack of cohesion between cornified cells. A marked decrease in the quantity of sebaceous material and bacteria was also evident within the comedones.Keywords
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