Sexual behavior of prepuberal male and female rats treated with gonadal hormones.

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Abstract
Following up an earlier study (by C. P. Stone, 1940) which suggested that the adult pattern of [male] sexual response might have been induced in rats < 29 days old had androgen been administered earlier, an attempt was made with 4 [male] animals injected with 1 mg. androgen in 0.2 ml. sesame oil daily from age 14 days. 2 litter controls were injd. with 0.2 ml. sesame oil without hormone. Two $ animals were injected with 100 R.U. of estrogen from day 14 and at irregular intervals; 2 others received these injns. at day 15 and on at irregular intervals. Certain aspects of the sexual response of the [male][male] were noted in both exptl. and control [male][male] at about the 21st day (sexual clasp). The complete copulatory pattern (sexual clasp, palpation with pelvic thrusts, and distinctive dismounting) was observed in the exptl. [male][male] at 21-29 days; ejaculation (copulation pattern with modified dismounting response) was observed in 2 exptl. animals at 27 and 29 days. The complete copulatory pattern in the exptl. animals antedated by about 30 days the normal appearance of this behavior in this colony. The [female][female] all showed lordosis, "the ultimate criterion of sexual receptivity" at 21-25 days of age (the response normally appearing at about 60 days). All [female][female] exhibited the [male] sexual clasp response, and 2 showed the palpation-with-pelvic-thrust behavior.

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