OBSERVATIONS ON THE FATE OF SODIUM SULFATE INJECTED INTRAVENOUSLY IN MAN 1
Open Access
- 1 May 1936
- journal article
- research article
- Published by American Society for Clinical Investigation in Journal of Clinical Investigation
- Vol. 15 (3) , 301-311
- https://doi.org/10.1172/jci100779
Abstract
Na2SO4 in hypertonic solution was injected intraven. in normal men and patients with chronic nephritis. Doses ranged from 1.3 to 20 gms. and were in most cases accompanied by NaCNS. Urinary excretions of Na and of SO4 ran parallel, the rate being proportional to the serum concn. The latter suggested that the injected salt was distributed like NaCNS, i.e., in the interstitial fluid only. The changes observed at the same time in the concns. of the principal electrolytes of serum indicated that shifts of water without Na or Cl between tissue cells and interstitial fluid were responsible for the readjustment of the osmotic equilibrium.This publication has 10 references indexed in Scilit:
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