The Genetic Legacy of Paleolithic Homo sapiens sapiens in Extant Europeans: A Y Chromosome Perspective
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- 10 November 2000
- journal article
- review article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 290 (5494) , 1155-1159
- https://doi.org/10.1126/science.290.5494.1155
Abstract
A genetic perspective of human history in Europe was derived from 22 binary markers of the nonrecombining Y chromosome (NRY). Ten lineages account for >95% of the 1007 European Y chromosomes studied. Geographic distribution and age estimates of alleles are compatible with two Paleolithic and one Neolithic migratory episode that have contributed to the modern European gene pool. A significant correlation between the NRY haplotype data and principal components based on 95 protein markers was observed, indicating the effectiveness of NRY binary polymorphisms in the characterization of human population composition and history.Keywords
This publication has 25 references indexed in Scilit:
- The Refugial DebateScience, 2000
- Y‐chromosome specific YCAII, DYS19 and YAP polymorphisms in human populations: a comparative studyAnnals of Human Genetics, 1999
- An Asian–Native American paternal lineage identified by RPS4Y resequencing and by microsatellite haplotypingAnnals of Human Genetics, 1999
- The Emerging Tree of West Eurasian mtDNAs: A Synthesis of Control-Region Sequences and RFLPsAmerican Journal of Human Genetics, 1999
- mtDNA Analysis Reveals a Major Late Paleolithic Population Expansion from Southwestern to Northeastern EuropeAmerican Journal of Human Genetics, 1998
- Phylogeography of mitochondrial DNA in western EuropeAnnals of Human Genetics, 1998
- Statistical properties of the variation at linked microsatellite loci: implications for the history of human Y chromosomes [published erratum appears in Mol Biol Evol 1997 Mar;14(3):354]Molecular Biology and Evolution, 1996
- Sequence variation of the human Y chromosomeNature, 1995
- The archeology of modern human originsEvolutionary Anthropology, 1992
- Synthetic Maps of Human Gene Frequencies in EuropeansScience, 1978