Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development
Open Access
- 10 April 2007
- journal article
- Published by Springer Nature in BMC Biology
- Vol. 5 (1) , 15
- https://doi.org/10.1186/1741-7007-5-15
Abstract
The pygopus gene of Drosophila encodes an essential component of the Armadillo (β-catenin) transcription factor complex of canonical Wnt signaling. To better understand the functions of Pygopus-mediated canonical Wnt signaling in kidney development, targeted mutations were made in the two mammalian orthologs, Pygo1 and Pygo2.Keywords
This publication has 41 references indexed in Scilit:
- Comprehensive microarray analysis of Hoxa11/Hoxd11 mutant kidney developmentDevelopmental Biology, 2006
- Nucleo-cytoplasmic distribution of β-catenin is regulated by retentionJournal of Cell Science, 2006
- The renin–angiotensin system in the development of the congenital anomalies of the kidney and urinary tractCurrent Opinion in Pediatrics, 2006
- Maternal Wnt11 Activates the Canonical Wnt Signaling Pathway Required for Axis Formation in Xenopus EmbryosCell, 2005
- Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression AnalysisScience, 2004
- Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling componentGenomics, 2004
- Autosomal recessive renal glucosuria attributable to a mutation in the sodium glucose cotransporter (SGLT2)Human Genetics, 2002
- Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodMethods, 2001
- Acre-transgenic mouse strain for the ubiquitous deletion ofloxP-flanked gene segments including deletion in germ cellsNucleic Acids Research, 1995
- Cell-adhesion molecule uvomorulin during kidney developmentDevelopmental Biology, 1985