Monoclonal antibodies to human myelomonocyte differentiation antigens in the diagnosis of acute myeloid leukemia
- 1 December 1984
- journal article
- research article
- Published by Springer Nature in Medical Oncology and Tumor Pharmacotherapy
- Vol. 1 (4) , 257-262
- https://doi.org/10.1007/bf02934532
Abstract
The immunological definition of malignant lymphatic cells has already been routinely applied by many laboratories over a number of years. Today it is clear and undisputed that the phenotypic data obtained in that way are often very useful and supporting. The immunological definition of non-lymphoid leukemias is not yet as far advanced. Additional surface markers for the recognition of poorly differentiated non-lymphoid cells are clearly needed. In this paper ten monoclonal antibodies to myeloid surface antigens are described. It is hoped that they are a useful addition to the presently available relatively small panel of well studied myeloid surface markers which are displayed by immature malignant blast cells.Keywords
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