Primidone (Mysoline) in the Treatment of Epilepsy

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Abstract
THE first report dealing with the use of primidone (Mysoline) in the treatment of epilepsy was presented in 1952 by Handley and Stewart.1 Many other investigators2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 subsequently used this drug for the control of epileptic seizures. In 1953 Doyle and Livingston8 analyzed the results obtained in 100 patients with epilepsy who had been given primidone for periods of three months to one year. The purpose of the present paper is to report our findings in a larger group of patients who received this drug for a much longer period.Material for StudyThe drug was administered to 486 patients who . . .