Thymus irradiation for myasthenia gravis.

Publisher Website
Google Scholar
Abstract
Patients (28) with progressive myasthenia gravis without thymoma received treatment of 3000 rads (30 Gy) [grays] to the anterior mediastinum, and a followup was conducted for 5-18 yr. Patients (24) had generalized myasthenia, and 4 had ocular myasthenia gravis. Twenty patients with generalized myasthenia survived the several month post-treatment period and improved, but 4 died during that period. The improvement lasted a median of 1.5 yr, and older patients had longer remissions than younger patients. The 4 patients who had ocular myasthenia did not change after treatment. Mediastinal irradiation produces a temporary remission in generalized myasthenia.

This publication has 2 references indexed in Scilit: