Hepatitis in the Marmoset, Saguinus mystax

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Abstract
Summary The marmoset, Saguinus mystax, developed signs of disease similar to human hepatitis when inoculated with marmoset sera containing Deinhardt's hepatitis agent, or sera from patients with infectious hepatitis but not when inoculated with serum containing hepatitis-associated antigen or with partially purified antigen. The evidence of disease were 3- to 10-fold increase above normal SGPT levels and histologic changes of single liver cell necroses with periportal lymphocytic infiltration. Hepatitis-associated antigen was not found in any marmoset sera by complement-fixation tests or electron microscopy.

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