Highly enantioselective aldol reaction: development of a new chiral auxiliary from cis-1-amino-2-hydroxyindan
- 1 January 1992
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- Vol. 1992 (22) , 1673-1674
- https://doi.org/10.1039/c39920001673
Abstract
Boron enolates obtained from optically active oxazolidinone derivative of cis-1-amino-2-hydroxyindan are reacted with various aldehydes to provide highly enantioselective aldol products in good yields.Keywords
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- Benzocycloalkyl amines as novel C-termini for HIV protease inhibitorsJournal of Medicinal Chemistry, 1991