Hypotensive Effect ofCrataegus oxyacantha
- 1 January 1987
- journal article
- research article
- Published by Taylor & Francis in International Journal of Crude Drug Research
- Vol. 25 (4) , 216-220
- https://doi.org/10.3109/13880208709055196
Abstract
The hypotensive effect of the herb Crataegus oxyacantha was investigated in vivo using normal anaesthetised rats. An aqueous extract of Crataegus oxyacantha leaves was found to produce a significant decrease in the systolic, diastolic and mean blood pressure, but no effect was noticed on heart rate. The hypotensive effect was dose dependent and reversible with a median effective dose of 31 mg/kg. It seems that the hypotensive effect of Crataegus oxyacantha is not mediated via adrenergic, muscarinic or histaminergic receptors.This publication has 3 references indexed in Scilit:
- The molecular basis of neurotransmission at the muscarinic receptorBiochemical Pharmacology, 1981
- beta-Adrenergic Receptor Subtypes: Properties, Distribution, and RegulationAnnual Review of Neuroscience, 1981
- Crataegus Oxyacantha in HypertensionBMJ, 1939