Accuracy of breeding values of 'unrelated' individuals predicted by dense SNP genotyping
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Open Access
- 11 June 2009
- journal article
- research article
- Published by Springer Nature in Genetics Selection Evolution
- Vol. 41 (1) , 35
- https://doi.org/10.1186/1297-9686-41-35
Abstract
Recent developments in SNP discovery and high throughput genotyping technology have made the use of high-density SNP markers to predict breeding values feasible. This involves estimation of the SNP effects in a training data set, and use of these estimates to evaluate the breeding values of other 'evaluation' individuals. Simulation studies have shown that these predictions of breeding values can be accurate, when training and evaluation individuals are (closely) related. However, many general applications of genomic selection require the prediction of breeding values of 'unrelated' individuals, i.e. individuals from the same population, but not particularly closely related to the training individuals.Keywords
This publication has 23 references indexed in Scilit:
- Invited Review: Reliability of genomic predictions for North American Holstein bullsJournal of Dairy Science, 2009
- Predicting Unobserved Phenotypes for Complex Traits from Whole-Genome SNP DataPLoS Genetics, 2008
- Accuracy of Predicting the Genetic Risk of Disease Using a Genome-Wide ApproachPLOS ONE, 2008
- Genome-wide association analysis identifies 20 loci that influence adult heightNature Genetics, 2008
- Accuracy of Genomic Selection Using Different Methods to Define HaplotypesGenetics, 2008
- The Impact of Genetic Relationship Information on Genome-Assisted Breeding ValuesGenetics, 2007
- Genome Partitioning of Genetic Variation for Height from 11,214 Sibling PairsAmerican Journal of Human Genetics, 2007
- Prediction of individual genetic risk to disease from genome-wide association studiesGenome Research, 2007
- Recent human effective population size estimated from linkage disequilibriumGenome Research, 2007
- Asymptotic rates of response from index selectionAnimal Science, 1989