Characterization of In 100 , a New Integron Carrying a Metallo-β-Lactamase and a Carbenicillinase, from Pseudomonas aeruginosa
Open Access
- 1 January 2005
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 49 (1) , 451-453
- https://doi.org/10.1128/aac.49.1.451-453.2005
Abstract
In100, a new integron carrying a carbapenemase gene (blaVIM-2) associated with a carbenicillinase (blaP1b) and aminoglycoside resistance genes (aacA4 and aadA2), was detected in a Pseudomonas aeruginosa clinical isolate. The particular gene cassette organization of In100 seems to reflect the evolution of antibiotic usage in therapeutics.Keywords
This publication has 25 references indexed in Scilit:
- bla VIM-7 , an Evolutionarily Distinct Metallo-β-Lactamase Gene in a Pseudomonas aeruginosa Isolate from the United StatesAntimicrobial Agents and Chemotherapy, 2004
- Antimicrobial Resistance Genes in Enterotoxigenic Escherichia coli O149:K91 Isolates Obtained over a 23-Year Period from PigsAntimicrobial Agents and Chemotherapy, 2003
- Genetic characterization of a novel metallo- -lactamase gene, blaIMP-13, harboured by a novel Tn5051-type transposon disseminating carbapenemase genes in Europe: report from the SENTRY worldwide antimicrobial surveillance programmeJournal of Antimicrobial Chemotherapy, 2003
- Spread of Integron-Associated VIM-Type Metallo-β-Lactamase Genes among Imipenem-Nonsusceptible Pseudomonas aeruginosa Strains in Greek HospitalsJournal of Clinical Microbiology, 2003
- Metallo-β-Lactamase VIM-2 in Clinical Isolates ofPseudomonas aeruginosafrom PortugalMicrobial Drug Resistance, 2002
- Efficiency of Recombination Reactions Catalyzed by Class 1 Integron Integrase IntI1Journal of Bacteriology, 2001
- Characterization of Class 1 Integrons from Pseudomonas aeruginosa That Contain the bla VIM-2 Carbapenem-Hydrolyzing β-Lactamase Gene and of Two Novel Aminoglycoside Resistance Gene CassettesAntimicrobial Agents and Chemotherapy, 2001
- Characterization of the Metallo-β-Lactamase Determinant of Acinetobacter baumannii AC-54/97 Reveals the Existence of bla IMP Allelic Variants Carried by Gene Cassettes of Different PhylogenyAntimicrobial Agents and Chemotherapy, 2000
- Characterization of VIM-2, a Carbapenem-Hydrolyzing Metallo-β-Lactamase and Its Plasmid- and Integron-Borne Gene from a Pseudomonas aeruginosa Clinical Isolate in FranceAntimicrobial Agents and Chemotherapy, 2000
- Mechanisms of resistance to the carbapenemsJournal of Antimicrobial Chemotherapy, 1995