Docking Interactions Induce Exposure of Activation Loop in the MAP Kinase ERK2
Open Access
- 30 June 2006
- Vol. 14 (6) , 1011-1019
- https://doi.org/10.1016/j.str.2006.04.006
Abstract
No abstract availableKeywords
Funding Information
- Welch Foundation
- Biological and Environmental Research (W-31-109-ENG-38)
- National Institutes of Health (DK46993, I1128)
- Argonne National Laboratory
- U.S. Department of Energy
This publication has 34 references indexed in Scilit:
- The Ste5 Scaffold Allosterically Modulates Signaling Output of the Yeast Mating PathwayScience, 2006
- Tethering: Fragment-Based Drug DiscoveryAnnual Review of Biophysics, 2004
- Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125The EMBO Journal, 2004
- Signalling specificity of Ser/Thr protein kinases through docking-site-mediated interactionsBiochemical Journal, 2003
- Crystal Structures of MAP Kinase p38 Complexed to the Docking Sites on Its Nuclear Substrate MEF2A and Activator MKK3bMolecular Cell, 2002
- Identification of Two Distinct Regions of p38 MAPK Required for Substrate Binding and PhosphorylationBiochemical and Biophysical Research Communications, 1999
- A MAP kinase docking site is required for phosphorylation and activation of p90rsk/MAPKAP kinase-1Current Biology, 1999
- Crystallography & NMR System: A New Software Suite for Macromolecular Structure DeterminationActa Crystallographica Section D-Biological Crystallography, 1998
- Activation Mechanism of the MAP Kinase ERK2 by Dual PhosphorylationCell, 1997
- Allosteric enzymes as models for chemomechanical energy transducing assembliesThe FASEB Journal, 1996