The effect of aspirin on peripheral haemodynamic changes following submaximal exercise in normal volunteers
- 1 August 1984
- journal article
- research article
- Published by Oxford University Press (OUP) in Cardiovascular Research
- Vol. 18 (8) , 511-513
- https://doi.org/10.1093/cvr/18.8.511
Abstract
Eight normal healthy volunteers participated in a study to determine the effect of 1800 mg of aspirin on the peripheral haemodynamic changes that occur following upright exercise. Aspirin reduced the extent of calf hyperaemia (p<0.05) and accentuated the reduction in forearm blood flow (p<0.05) following exercise. It had no effect on either calf or forearm blood flow at rest. These results indicate that aspirin, possibly by inhibiting prostacyclin producion, modifies the circulatory changes following upright exercise.Keywords
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