Synthesis of P-Thioadenylyl (2′-5′) Adenosine and P-Thioadenylyl (2′-5′)-P-Thioadenylyl-(2′-5′)-Adenosine
- 1 January 1987
- journal article
- abstracts
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 6 (1-2) , 513-516
- https://doi.org/10.1080/07328318708056272
Abstract
Dimer and trimer adenylates with 2′-5′ phosphorothioate linkages were synthesized via the phosphoramidite method using p-nitrophenyl-ethyl group for phosphate protection and followed by sulfur oxidation. The various diastereoisomers were separated and characterized.Keywords
This publication has 6 references indexed in Scilit:
- Synthesis of P-thioadenylyl-(2'-5')-adenosine and P-thioadenylyl-(2'-5')-P-thioadenylyl-(2'-5')-adenosineThe Journal of Organic Chemistry, 1984
- Analogs of (A2'p)nA. Correlation of structure of analogs of ppp(A2'p)2A and (A2'p)2A with stability and biological activity.Journal of Biological Chemistry, 1982
- Synthesis of inosinate trimer I2′p5′I2′pt′I and tetramer I2′p5′I2′p5′I2′p5′ITetrahedron Letters, 1982
- Synthese du trimere de la β--xylofurannosyl-9 adenine a liaisons internucleotidiques 2′→5′.Tetrahedron Letters, 1981
- Synthesis of 2′-end modified 2′-5′-adenylate trimersTetrahedron Letters, 1980
- Synthesis and properties of 3′-deoxyadenylate trimer dA2′p5′A2′p5′ATetrahedron Letters, 1980