Chlorpromazine Treatment of Disturbed Monkeys

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Abstract
Four rhesus monkeys which were subjected to partial social isolation during the first 11 months of life and which had consistently exhibited patterns of grossly abnormal behavior during the 1½ years prior to the current study were treated with chlorpromazine.Three of the four subjects showed significant decreases in their self-disturbance behaviors on 7.5 mg/day of chlorpromazine given as the liquid concentrate by nasogastric intubation. The fourth subject showed no change. Plasma chlorpromazine levels confirmed absorption of the drug in all subjects.

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